Carnitine and its derivatives exist in a carnitine “pool” in the body. Cellular enzymes and transporters rapidly convert the carnitine to the required form and transport it to the tissues. Carnitine and its derivatives play a key role in fat, carbohydrate, and protein metabolism and energy production and are critical components for mitochondrial metabolism. Acetyl-L-carnitine (ALC) is the most important derivative of carnitine and occurs naturally in the body. Because ALC is considered to have greater bioavailability and is therefore more able to cross neurological membranes, it is the preferred form to take for promoting neurological health.

The levels of carnitine and its derivatives are critical to normal biological functioning. Carnitine is present in the diet in red meats and dairy products, and humans can make carnitine from the amino acids lysine and methionine. However, carnitine deficiency can occur with metabolic disorders, and in conditions such as diabetic neuropathy (nerve pain) and other complications of diabetes.

ALC has been studied in various conditions including neurological and cognitive disorders such as Alzheimer’s, dementia, depression, neuropathies, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica.

• The most important derivative of carnitine, and the preferred form to take, as it is the most bioavailable
• Able to cross the blood-brain barrier
• Has many neurological benefits, including cognitive ability, memory, and mood
• Naturally occurring nutrient, free from toxic effects

Acetyl-L-carnitine is the most abundant naturally occurring derivative of carnitine. ALC helps the body produce energy at the cellular level; regulates carbohydrate, lipid and protein metabolism; facilitates fatty acid entry into the mitochondria; and maintains the homeostasis of coenzyme A. ALC also displays potent antioxidant effects and supports repair mechanisms. ALC has been shown to support heart and brain function, muscle movement, and numerous other body processes.

ALC protects and enhances the activity of neurons and transmitters in the mitochondria and reduces oxidative stress. By improving cellular function and effi ciency in the mitochondria, ALC stabilizes the fl uidity and function of cell membranes, and improves energy production. ALC is involved in peripheral nerve regeneration and has shown promise in improving neuropathy. Because ALC is able to cross the blood-brain barrier it is able to exert its neuroprotective effects in the brain. Studies have shown ALC can improve cognitive performance and mood by protecting against oxidative stress and reducing or blocking the neuronal death that occurs with dementia and other neurodegenerative conditions.

Supplementation with ALC may be useful in a broad range of conditions, including Alzheimer’s, dementia, age-related memory loss and depression, fatigue, diabetic neuropathy, and cardiovascular disease.

Each Capsule Contains:
Acetyl-L-Carnitine (N-Acetyl L-carnitine hydrochloride)	500 mg

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica.