AOR Citicoline is cytidine 5'-diphosphate choline. Citicoline plays a crucial role in the Kennedy pathway, by which the body synthesizes phosphatidylcholine (PC) and, ultimately, other phospholipids, such as phosphatidylserine (PS). By supporting the body's synthesis of new phospholipids in youthful, physiological balance, Citicoline supports brain structure. Extensive research supports the role of Citicoline in supporting optimal cognitive function. Trials have documented the powerful support provided by Citicoline supplementation in Alzheimer's disease, stroke, dementia associated with Parkinson's disease, and head trauma, and that it improves the odds of a good outcome after high-risk brain surgery.
Citicoline works by enhancing the brain's ability to synthesize its own phospholipids. Citicoline's real "business end" is its cytidine group. Studies show that cytidine itself, or cytidine delivered as Citicoline, boosts brain and neural PS by 37.2%, PC by 22-30%, PI by 16%, and PE by 11-13%. By supporting the brain's ability to make its own phospholipids, Citicoline increases levels of all phospholipids in neural membranes - yet the healthy, youthful proportions of the various phospholipids are not altered.
Citicoline is helpful with many non-brain conditions grounded in neurological dysfunction. Glaucoma, for instance, is most commonly the result of a buildup of pressure from the fluid in the eye (intraocular pressure), which literally squeezes the nerves that leave the eyeball, causing them to lose their supply of nutrients and slowly starve. In an open trial, 36 patients with glaucoma were given one gram of Citicoline daily for ten days. While the study was too short to assess any improvement in symptoms, the researchers did find that Citicoline "acts positively on the glaucomatous optic nerve damage" and led to "favorable neurotrophic [nerve-nourishing] effects."
Likewise, amblyopia, or "lazy eye," is ultimately a neurological disorder, although always associated with some other problem with visual function (such as a misalignment of the focus of the two eyes). Amblyopia develops when the nerve cells, which connect one eye to the brain are literally turned off, because the sensory messages the poorer eye is sending don't match up with those being sent by the dominant eye. After years of being deactivated, the nerves leading to the amblyopic eye can ultimately cause that eye to go fully blind.
Again, Citicoline may offer hope. Researchers have performed several trials in patients with amblyopia, which have confirmed that Citicoline significantly improves both symptoms and neurological function, and can be used to increase the effectiveness of occlusion (the standard therapy for "lazy eye")
AOR Citicoline is enhancing the brain's ability to synthesize its own phospholipids. It provides powerful support in Alzheimer's disease, stroke, dementia associated with Parkinson's disease, head trauma, conditions grounded in neurological dysfunction like Glaucoma and lazy eyes.
|
*Dietary Reference Intake not established. Other ingredients: microcrystalline cellulose. Capsule: hypromellose, water.
AOR guarantees that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish or shellfish.
Suggested Use Take two to four capsules daily, or as directed by a qualified health consultant.
Main Applications As reported by literature: • Cognitive support. • Age-associated memory impairment (AAMI). • Support for nerves of the eye.
Source Biofermentation.
Pregnancy / Nursing No studies have been conducted; best avoid.
Cautions None known.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
|